Featured Article Target ALS Launches “Behind Every Breakthrough” Campaign for ALS Awareness Month to Spotlight Progress and People Driving ALS Research Forward READ MORE SearchAll CategoriesALS & Other DiseasesALS DiagnosisAnnouncementsAnnual MeetingChangemakersCollaborationCore FacilitiesEducational BlogsFrom Our TeamFrom Target ALSFrom the Innovation EcosystemFundraising CampaignsHear From the ScientistsIn the NewsInspiring StoriesNewsNewsletters & ReportsScience on TargetSpartan ChallengeSupport for ALSThought LeadersTrendsUncategorizedUnderstanding ALSUnderstanding the ScienceVideo LibraryVoices of ALSNewest to OldestOldest to Newest Pioneering the Next Generation of ALS Therapeutics: Announcing the 2025 Novel Modalities Consortia Grantees READ MORE March 2025 Newsletter READ MORE Bridging Worlds: Volkan Granit and the Unique Collaborative Spirit of Target ALS READ MORE Target ALS Highlighted in New Case Study Released by Harvard Kennedy School Focused on Innovative Model for Collaborative Medical Research READ MORE A Trailblazer in Neuroscience and Biotech Leadership READ MORE Unveiling the Power of Diversity: The Impact of Research in Colombia READ MORE Women in Science at Target ALS: Breaking Barriers, Driving Discovery READ MORE Research, Resilience, and Representation: Dr. Leeanne McGurk Weighs In READ MORE Science on Target March 2025 Newsletter READ MORE Perseverance and Prevailing: A Seven-Year Journey in Neuroscientific Innovation READ MORE From Paris, With Love for Science: Dr. Latouche’s Groundbreaking ALS Research READ MORE Transforming the Future of ALS Research: Reflections from Our Community Outreach Event in Arizona READ MORE Unveiling the Power of Diversity: The Impact of Research in Colombia READ MORE CRISPR: A Powerful Tool Used to Advance ALS Research READ MORE Empowering Puerto Rico’s ALS Community: The Impact of Research READ MORE 2024 Year In Review READ MORE ALS Arizona: Empowering Lives, Strengthening Community, and Advancing Progress READ MORE Mind the Gap: Sabine Liebscher is Connecting the Dots of ALS READ MORE Progress and Impact: 2022 Basic Biology Grants READ MORE Tofersen Shows Promising Results in SOD1 ALS Treatment—A New Hope for Genetic Therapies READ MORE Unveiling the Path to ALS Therapies: A Journey from Flies to Humans READ MORE Accelerating ALS Research: A Scientist’s Experience with the Target ALS Data Engine READ MORE Digital Biomarkers – An Opportunity to Overcome the Limits of Traditional Rating Scales? READ MORE Researchers Report on the Opposing Roles of p38α Phosphorylation and Protein Arginine Methyltransferase 1 (PRMT1) Methylation in TDP-43 Proteinopathy READ MORE Together For Rare: Judith Chavira on Diversity in ALS Research READ MORE Diane Pascot: A Journey of Hope and Courage READ MORE January 2025 Newsletter READ MORE ALS Disease Statistics: Insights from Latest Research READ MORE Advancing ALS Research: Key Insights and Breakthroughs from the 2024 International Symposium on ALS/MND READ MORE Advancing ALS Research with Stem Cell Resources and Targeted Reagents: The Role of Target ALS in the Quest for Effective Treatments READ MORE December 2024 Newsletter READ MORE Collaborating for Progress: ALS United Greater New York and Target ALS READ MORE Dan Doctoroff: From Transforming New York City to Building a World Where Everyone with ALS Lives READ MORE Navigating Life After an ALS Diagnosis: Understanding Progression, Stages, and What to Expect READ MORE November 2024 Newsletter READ MORE Target ALS Attends NEALS Conference: Insights into Groundbreaking Research READ MORE Science on Target November 2024 Newsletter READ MORE A Labor of Love: Theresa Whitlock-Wild’s Unwavering Commitment to Families Affected by ALS READ MORE A Father’s Fight, A Daughter’s Strength: Navigating Life with ALS READ MORE Addressing Inequities in ALS Healthcare: The Critical Need for Diversity in Research READ MORE Veterans and ALS: A Critical Population for Advancing Research READ MORE A Race Against Time: A Story of ALS and Caregiving READ MORE Breaking Down Barriers in ALS Research: New Validated pTDP-43 Antibody Now Available Globally READ MORE Five Innovative Collaborative Projects Awarded Biomarker Consortia Grant Funding READ MORE Dan Doctoroff discusses future of New York, pushes for ALS funding on Spectrum News READ MORE Target ALS featured in ALS News Today: ALS respiratory data now available to researchers worldwide READ MORE Target ALS October 2024 Newsletter READ MORE Two Studies Awarded Funding to Accelerate Novel ALS Therapies Through In-Vivo Proof-of-Concept READ MORE Target ALS Partners with ZEPHYRx to Enhance Global ALS Research Through Data Integration READ MORE Updates from our Research Cores: Expanding our Cellular Model Toolkit READ MORE Target ALS September 2024 Newsletter READ MORE Science on Target: Target ALS Postmortem Tissue Core Facilitates Groundbreaking Research on SOD1 Protein Aggregation READ MORE Target ALS and Modality.AI Collaborate in Multimodal Study of ALS READ MORE The Target ALS Data Engine Just Got Bigger: New Data Available for Mining READ MORE Biomarker Milestone Achieved: Target Identification READ MORE Announcing the Recipients of the 2024 In Vivo Target Validation Grants in Collaboration with Biospective READ MORE Announcing the Recipients of the Basic Biology Consortia Grant READ MORE A PATH TO A WORLD WHERE EVERYONE LIVES – Highlights from the 2024 ALS Annual Meeting READ MORE Letter From Our Founder: Reflecting on 2024 Target ALS Annual Meeting READ MORE Letter From Our CEO: 2024 Target ALS Annual Meeting Remarks READ MORE Breakthroughs in Biomarker Research: Insights From Our 2024 Annual Meeting READ MORE Identifying Novel Drug Targets: Expanding the Horizons of ALS Treatment READ MORE 2024 Neurology Resident Grants Recipients Announced READ MORE Drug Discovery and Development: A Glimpse into the Future of ALS Treatment READ MORE Dan Doctoroff Against ALS – Time Magazine READ MORE New Natural History Study Collection Added to Target ALS Data Portal READ MORE Target ALS raises $250 million to accelerate ALS research – ALS News Today READ MORE Target ALS Achieves Extraordinary $250 Million Capital Campaign Goal to Accelerate ALS Research READ MORE Target ALS Launches Groundbreaking Data Portal with DNAstack and Verily to Fuel Breakthroughs in ALS Research READ MORE Target ALS Has Been Named an Official Charity Partner for the 2024 TCS New York City Marathon READ MORE Biofluid Samples from Target ALS Natural History Study Available for Global Distribution to Advance ALS Research READ MORE Target ALS 2023 Annual Report READ MORE Everyone Lives: Target ALS Newsletter Winter 2023/2024 READ MORE Target ALS Celebrates 10 Years: A Decade in Review READ MORE “His Mind Helped Rebuild New York. His Body is Failing Him.” – Dan Doctoroff featured in the New York Times READ MORE Former NYC deputy mayor raises millions for ALS research while facing his own mortality – PBS News READ MORE Everyone Lives: Target ALS Newsletter Fall 2023 READ MORE Why Michael Bloomberg’s Former Deputy Mayor is Raising $250 Million for ALS Research – People READ MORE Target ALS Has Been Named an Official Charity Partner for the 2023 TCS New York City Marathon READ MORE “What the Builder Built”- Dan Doctoroff featured in Curbed READ MORE The Ultimate Guide to Cognitive Impairment, Dementia, and ALS READ MORE Therapeutic Target HDAC6 and ALS READ MORE How FUS Fits into the Bigger RNA Protein Picture READ MORE RNA Therapy for ALS: A Promising Treatment READ MORE Epidemiology of ALS: Incidence, Prevalence, and Suspected Clusters READ MORE What is AAV for Gene Therapy? READ MORE Juvenile ALS: How Common is ALS in Your 20s? READ MORE The Missing Piece of ALS Research: Biomarkers READ MORE How Does an ALS Muscle Biopsy Help Researchers? READ MORE Target ALS 2021 Annual Report READ MORE How ASO Research May Help Nano-Rare ALS Patients READ MORE How Dan Doctoroff Lives With a Terminal Diagnosis – Bloomberg READ MORE The C9orf72 ALS Connection READ MORE The Role of Stress Granules in ALS READ MORE Benefits of Using Cerebrospinal Fluid Samples in Medical Research READ MORE Target ALS and Alzheimer’s Drug Discovery Foundation Announce Award Recipients for Biomarker Research READ MORE The Effects of ALS on the Digestive System READ MORE How Upper and Lower Motor Neurons Relate to ALS READ MORE Understanding the Science with Dan Elbaum, Ph.D. READ MORE Understanding the Science with Merit Cudkowicz, Ph.D. READ MORE Understanding the Science with Sarah Glass, Ph.D. READ MORE Understanding the Science with Penny Dacks READ MORE Understanding the Science with Leonard Petrucelli READ MORE Understanding the Science with Aarti Sharma READ MORE Fireside Chat with Founder, Dan Doctoroff READ MORE Understanding the Science with Robert Bowser, Ph.D. READ MORE Understanding the Science with Stanley Crooke READ MORE Understanding the Science with Susan Dickinson of AFTD READ MORE Target ALS Annual Meeting 2022 | Dan Doctoroff READ MORE Understanding the Science – Spotlight on Biomarkers READ MORE Interview with Emanuele Buratti, Ph.D. | 2023 Target ALS Annual Meeting READ MORE Interview with Jenna Gregory, Ph.D. | 2023 Target ALS Annual Meeting READ MORE Interview with Alexander McCampbell, Ph.D.| 2023 Target ALS Annual Meeting READ MORE Interview with Fanny Elahi, M.D., Ph.D | 2023 Target ALS Annual Meeting READ MORE Interview with Elizabeth Buttermore, Ph.D. | 2023 Target ALS Annual Meeting READ MORE Interview with Dr. Stefan McDonough | 2023 Target ALS Annual Meeting READ MORE Interview with Sarah Glass, Ph.D. | 2023 Target ALS Annual Meeting READ MORE The Postmortem Tissue Core Team Shares Why They Do What They Do READ MORE Interview with Matt Disney, Ph.D. | 2023 Target ALS Annual Meeting READ MORE Interview with Johannes Troger, D.SC. | 2023 Target ALS Annual Meeting READ MORE Interview with Dr. Dorothy Schafer | 2023 Target ALS Annual Meeting READ MORE Interview with Dr. Jonathan Cooper Knock | 2023 Target ALS Annual Meeting READ MORE Interview with Hemali Phatnani, Ph.D. | 2023 Target ALS Annual Meeting READ MORE A Family’s Battle with ALS: Story of Hope and Determination READ MORE ALS Symptoms: What are the Most Common Symptoms and Diagnosis READ MORE ALS Genetic Mutations Explained READ MORE The Connection Between Dysphagia and ALS READ MORE Under the Microscope: Dr. Emanuele Buratti on the Role of TDP-43 in ALS Pathology READ MORE Target ALS Announces New Corporate Council Partnership Opportunity READ MORE ALS Muscle Twitching vs BFS Muscle Twitching: Knowing the Differences READ MORE Target ALS Issues Call For Proposals for ALS Biology-Focused Collaborative Projects READ MORE Leonard Florence Center for Living Offers Independence and Support for Individuals Living with ALS READ MORE Inaugural Rebecca Luker Courage Award of Recognition: Mark Calmes READ MORE Making Accessibility Accessible: John-boy’s Place and Windchime Wishes READ MORE Inaugural Rebecca Luker Courage Award of Recognition: Sandy Morris READ MORE Inaugural Rebecca Luker Courage Award of Recognition: Timothy Miller, MD/PhD READ MORE What is Bulbar-Onset ALS? Six Things to Know. READ MORE Inaugural Rebecca Luker Courage Award Unsung Hero Winner: Joumana Baroody READ MORE Winner of the Inaugural Rebecca Luker Courage Award: Merit E. Cudkowicz READ MORE n-Lorem Foundation and Columbia University Establish Silence ALS Initiative READ MORE Target ALS and Mitsubishi Tanabe Pharma America Announce Winner of the First Annual Rebecca Luker Courage Award READ MORE ALS in the Elderly: Recognizing ALS in Seniors READ MORE Interview with Dr. Joseph Lewcock | 2023 Target ALS Annual Meeting READ MORE ALS and Nutrition: How Diet Impacts ALS Patients READ MORE Sporadic ALS: Understanding Why ALS Occurs with no Family History READ MORE How ALS Affects Speech READ MORE Saying Goodbye to a Friend Who Battled ALS: Julie Giacobassi READ MORE What Do We Talk About When We Talk About Genetics? READ MORE It’s Not Just Physical: ALS, Dementia, Cognitive Impairment and Memory Loss READ MORE Diagnosing ALS: It’s Often a Year-Long Journey READ MORE False Positives and False Negatives: How ALS Can be Misdiagnosed READ MORE How to Help Someone with ALS: Tips for Friends, Family members and Caregivers READ MORE How ALS Research Studies Work READ MORE ALS and Other Motor Neuron Diseases: What’s the Difference? READ MORE The Stages of ALS: Framing the Progression of a Nonlinear Disease READ MORE Alzheimer’s Drug Discovery Foundation (ADDF) and Target ALS Announce Partnership to Accelerate Biomarker Discovery and Development READ MORE Thinking About Participating in a Clinical Trial? Here’s What You Need to Know READ MORE Giving Back Hope: Creating Resources for Children Affected by ALS READ MORE Under the Microscope: Dr. Dan Elbaum on the Role of STATHMIN-2 READ MORE Reversing ALS? It’s Still Early, but ASO Therapeutics Are Generating Optimism READ MORE Baseball, the Father of Neurology and Epidemiology: Connecting the ALS Dots READ MORE Under the Microscope: Gene Yeo on RNA-Directed Therapy for ALS Caused by a C9ORF72 Mutation READ MORE Understanding ALS-Related Genes Leads to New ALS Therapeutic Insights READ MORE Complex Decisions: Predictive Genetic Testing for Family Members READ MORE Under the Microscope: Dr. Philip Wong on Searching for TDP-43 Biomarkers READ MORE Giving in the Face of ALS: A Fight to Help the ALS Community Keep Living After Diagnosis READ MORE Top 4 Things You Need to Know About ALS READ MORE How a Research Idea Transforms Into a Clinical Trial READ MORE Similarities in Neurodegenerative Disorders May Lead to New, Common Therapies READ MORE Tiny Protein, Enormous Potential: Why TDP-43 Matters READ MORE Target ALS and Mitsubishi Tanabe Pharma America Announce Rebecca Luker Courage Award Series and Call for Nominations READ MORE Target ALS 2020 Annual Report READ MORE Under the Microscope: Christine Vande Velde on Seeking Solutions for Cellular Self Defense READ MORE Under the Microscope: Sami Barmada, M.D., Ph.D. on Biomarkers and Therapeutic Targets for ALS and FTD READ MORE Finding The Light Amidst ALS: Sunny Brous’ Story READ MORE The Power of Community + ALS: Bryan Rosica’s Story READ MORE To Dad, With Love: One Daughter’s Story of a Father’s ALS Journey READ MORE From an Arm Twitch To ALS Advocacy READ MORE Target ALS Announces “Becca,” a One-Night Only Streaming Concert Fundraiser Featuring Broadway’s Best-Known Stars, in Memory of Rebecca Luker READ MORE Target ALS Announces Second Round of 2020 Grant Recipients Focused on Discovering and Developing ALS Biomarkers READ MORE Target ALS Launches The First-Ever Comprehensive Research Initiative to Discover Urgently Needed ALS Biomarkers READ MORE Research Funding Decisions Made Fair; Independent Review is Key READ MORE We Salute You: Tom’s Life Was Defined By Much, But Not By ALS READ MORE Living Life to the Fullest: Eric’s Story of Giving ALS a Run for Its Money READ MORE Tripper’s Five Tips to Take on “The Toughest Challenge” in Support of ALS Research READ MORE ALS Charity Gets Creative During COVID-19 By Taking On ‘The Toughest Challenge’ READ MORE Under The Microscope: The Role of Genomics in ALS Research READ MORE Meet The Toughest Challenge For The Hardest Fight / Join Us to Make a Difference READ MORE 5 Answers About ALS From Our CEO READ MORE Our ROI: Impact to Date of the Target ALS Innovation Ecosystem READ MORE ‘The Unexpected Artist’: Guest Post by Ron Hoffman, Compassionate Care ALS Founder READ MORE ‘Never Say Invisible’: One Family’s Perspective on Living with ALS READ MORE UNDER THE MICROSCOPE: Why TDP-43 Matters So Much in ALS Research READ MORE Under the Microscope: Sophie Parmentier-Batteur on Interrogating a Protein Compound for Possible Therapeutic Approaches to ALS and FTD READ MORE UNDER THE MICROSCOPE: Ludo Van Den Bosch on Returning to Work, Exploring Therapeutic Strategies to Battle ALS & FTD READ MORE Searching for Information, a Media Resource Offers Credible, Compassionate News and Relatable Stories to the ALS Community READ MORE Under the Microscope: Fen-Biao Gao ofUMass Medical School Explains His Now-Funded Project Targeting Biomarkers and Disease Modifiers for ALS and FTD READ MORE Building a Safer Future: How Matt’s Place Foundation is Helping ALS Patients With Home Accessibility READ MORE Target ALS and AFTD Announce $5MM in Grants for Research Targeting Treatments and Biomarkers READ MORE Target ALS and The ALS Association Announce New TDP-43-Focused Biomarker Initiative READ MORE Target ALS Annual Meeting Canceled Due to the Spread of COVID-19 READ MORE Target ALS Expands Stem Cell Core to Include Innovative New Reporter Lines READ MORE What’s Next for Target ALS? A Preview of Our Work in 2020 READ MORE Thanks to Your Support: $35 Million Raised in 2019 READ MORE Target ALS Innovation Ecosystem Impact & Upcoming Initiatives READ MORE ALS/FTD Response Signals Resounding Desire for Collaboration READ MORE A Cancer Drug for ALS? Organization Forges Promising ALS Treatment, an Innovative Approach to Incubate Novel Therapeutics READ MORE NEWS: Target ALS-Funded Research Shows Promise in Slowing ALS Disease Progression Scientists Discover Method to Decrease Neuroinflammation and Extend Life Expectancy READ MORE 150 Years Later, Still No Effective Treatment for ALS. New Research Model Offers Hope READ MORE NEWS: Target ALS Biosample Recipients Identify Three Distinct Subtypes of ALS READ MORE Target ALS & AFTD Announce Groundbreaking Partnership to Spur Drug and Biomarker Development for ALS and FTD READ MORE The Boston Globe Features Target ALS Founder, Dan Doctoroff READ MORE Target ALS Awards Six Innovative Research Teams with Additional Target Discovery Funds READ MORE American Academy of Neurology and Target ALS Partner to Accelerate ALS Research READ MORE Case Study: Collaboration Accelerates Potential ALS Treatment READ MORE Case Study: Consortium Explores KPT-350 as a Potential Treatment for ALS READ MORE Target ALS Foundation Makes Human Stem Cell Lines Accessible to Researchers READ MORE Target ALS Providing Critical Tool to Study C9ORF72 Biology READ MORE Case Study: Biomarkers Offer Optimism for People with ALS READ MORE New Biomarker Study with Academic, Industry and Philanthropic Partners READ MORE Target ALS expands core facilities access to MDA development grant awardees READ MORE Target ALS Foundation Selects RUCDR Infinite Biologics READ MORE Partnership to Uncover Connection Between Ancient Retroviruses and ALS READ MORE Biogen and Target ALS Foundation Announce $20 Million Funding Challenge READ MORE The New York Times Features Daniel L. Doctoroff, Target ALS Founder READ MORE
