• Skip to primary navigation
  • Skip to main content
  • Skip to footer

Target ALS

A New York based ALS research organization that's leading the fight for a cure.

  • DONATE
  • About Us
    • Our Mission
    • Our Model
    • Our Impact
    • Our Founder
    • Our Team
    • Our Partners
  • For Scientists
    • Research Cores
      • Target ALS Data Engine
      • Longitudinal Biofluids Core
      • Human Postmortem Tissue Core
      • Stem Cell Core
      • Reagents Core
      • Animal Models Core
    • Funding Opportunities
    • Funded Projects
    • Annual Meeting
    • Science on Target Blog
    • FAQs for Researchers
  • Understanding ALS
    • About ALS
    • Understanding the Science
      • Glossary
      • FAQ
      • ALS 101
    • Voices of ALS
    • Video Library
  • Take Action
    • Support Geoff Greulich
    • The ALS Global Research Initiative (AGRI)
      • Global Natural History Study
      • Community Based Pop-Up Clinics
    • Ways to Give
    • Email Sign Up
    • Contact Us
    • Donate Now
  • News
    • Announcements
    • In the News
    • Newsletters & Reports

Grants for ALS Research & Drug Discovery

Our Focus

Target ALS funds investigators who collaborate across scientific disciplines and research constituencies to drive medical breakthroughs for the treatment of ALS.

By bringing together the right people, funding, tools, and resources, Target ALS is breaking down barriers that have existed for decades, amplifying and accelerating the ALS drug discovery and development process.

Our funding opportunities are open to investigators working worldwide.


Our Grantmaking Process

Submit LOIs
Review of LOIs
Invitation to submit research proposal
Submit research proposal
Review of research proposals by an independent panel of experts
Funding decisions announced
Release of funds

Open Funding Opportunities

researcher

Springboard Fellowship

Recently Closed Funding Opportunities

researcher

In Vivo Target Validation

Drug Discovery Consortia

Upcoming Funding Opportunities

Each year, the Target ALS team strategically designs funding opportunities to accelerate ALS research. Please find our upcoming 2025 grant programs below.

  • Springboard Fellowships – Launching June 2025

Participate in the Target ALS Mission

We encourage you to join our mission by using our core facilities or contacting us to discuss how we can help facilitate your work on ALS. To learn about our current and former grant recipients, visit our Funded Consortia page.

To stay up-to-date with Target ALS announcements, breaking news, and research articles, you can join our newsletter and follow us on LinkedIn.

FAQ

Eligibility

Are international applicants eligible to apply?

Yes, we welcome applicants from outside the USA for all of our funding opportunities.

What is a competitively-funded grant?

A competitively funded grant that is one that is awarded based on published funding opportunities on our website. In Vivo Target Validation grants are an exception to this rule and are not considered competitively funded grants. Target ALS also awards grants to further expand our Research Cores. These grants are not considered competitive. 

I already have an active Target ALS grant. Can I apply for another one?

Target ALS places restrictions on many of its funding opportunities, prohibiting applications from PIs that already have two or more competitively-awarded active Target ALS grants. We do this to encourage a greater diversity of applicants and ideas in our application pool. 

Can I submit more than one application to the same funding opportunity?

No. You can only submit one application for any given funding opportunity (with the exception of In Vivo Target Validation grants).

Can post-docs be Principal Investigators?

We expect that the Principal Investigator is someone who runs an academic research lab, or industry equivalent.

Can a Contract Resource Organization (CRO) be included as an applicant for a consortium grant and receive grant funding?

A CRO can be considered a consortium partner, but they do not qualify to meet the industry partner requirement in any Target ALS funding calls that require such a partner to participate.

Target ALS requires all consortium partners to sign an IP sharing agreement amongst themselves. Depending on the structure of the consortium and the work being performed by the CRO, having a CRO as a formal partner may be simple or it may be very complex. We recommend you evaluate the relative complexity in advance of submitting your application.

Application

Are figures included in the total page limit for an application?

Yes

Are references included in the total page limit for an application?

No

Budget

Will Target ALS enter into a confidentiality agreement with my company or institution to allow me to apply for a funding opportunity?

No. Target ALS staff and Independent Review Committee (IRC) members sign a confidentiality agreement with Target ALS to ensure all confidential information contained in grant applications remains confidential. Neither staff nor IRC members will enter into a separate agreement as a condition of application.

The application requires specific people to be named as fellows for the grant. Can I name these people at a later date, once they are hired?

You can put TBD into the fields, if you don’t already have candidates or need an approved grant before you are allowed to hire.

Does Target ALS fund indirect costs?

No, we do not fund indirect costs. We do permit up to 15% of the award to be allocated for research-associated direct costs. These costs must be specifically tied to the project being funded. Examples include: lab rent, tuition and fees for fellows, IT costs specifically related to the project, etc. These expenses must be specified in your budget.

Is there a cap for the Principal Investigator’s salary?

Yes. We adhere to the salary cap used by the NIH for Executive Level II, which is updated annually.

The budget requires a fellow for each lab to be dedicated to the project at 75% effort. Does the Target ALS grant have to cover 75% of their salary?

No. If you have other flexible sources of funding, you may use it to cover any part of the fellow’s salary. We are most concerned with ensuring a dedicated level of effort on the project.

I have an active Target ALS grant

Can I have a no-cost extension?

No-cost extensions require a scientific rationale and are evaluated on a case-by-case basis. A no-cost extension request should be submitted on institutional letterhead and should include:

  • Project title
  • Principal Investigator name and contact information
  • Grant number
  • Original project start date and end date
  • Award amount
  • Summary of progress made to date on the project.
  • A proposed new project end date.
  • A justification for the additional time requested. This should provide an explanation of what happened to necessitate the extension.
  • A completed Grant Expenditure Report showing how much of the grant funds have been spent to date.

No-cost extension requests should be submitted to Yuliya Rzad, Chief Grants Officer.

I did not spend all of the funds in the first year of my grant. Can I roll it over into the second year?

Yes. If you have been awarded a multi-year grant, unobligated funds may be rolled over from one year to the next.

Can I move funds from one budget category to another?

Yes. If you are moving 15% or less of the total grant award for that year, you can move the funds among budget categories as needed. You do not need our permission or approval to do so. If you want to move  more than 15% of the total grant award for that year, you will need to submit a budget amendment request. That request will need to be approved by Target ALS in advance of making any changes.

How do I submit a budget amendment request?

A budget amendment request should be submitted on institutional letterhead and should include:

  • Project title
  • Principal Investigator name and contact information
  • Grant number
  • Original project start date and end date
  • Award amount
  • Summary of progress made to date on the project.
  • A budget justification explaining the rationale for moving funds from one line to another or for increasing the award amount. This should include an explanation of how the budgetary changes impact the success of the project.
  • A revised grant budget.

Budget amendment requests should be submitted to Yuliya Rzad, Chief Grants Officer.

Is there a template for the financial report?

Yes. We provide a template for the financial report required from grantees. However, you are not required to use this template and can substitute your own format if you like.

Footer

Target ALS
  • Donate
  • Contact
  • Financial Reports
  • Call For Proposals
  • Annual Meeting
  • Privacy Policy
  • Credits

Follow Us

We are a 501(c)(3) public charity (EIN: 81-0756743), eligible to receive tax-deductible contributions that directly support our mission to break down barriers to ALS research to find effective treatments.

The Target ALS (TALS) website is intended for informational purposes only. Opinions expressed may not be that of TALS or its employees. For more information about our digital policies, click here.

© 2023 Target ALS Foundation, Inc.
Target ALS Foundation
244 Madison Avenue #1025
New York, NY 10016
(332) 333-4140
Steck Insights WordPress Consulting