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Target ALS

A New York based ALS research organization that's leading the fight for a cure.

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Reagents Core

C9orf72 Poly(GP) Monoclonal Antibody:

We have generated the monoclonal antibody against human poly(GP) protein translated from G4C2 RNA.  The antibody comes from two hybridoma clones, which are available to the ALS research community worldwide. Investigators interested in the more immunoreactive of the two purified poly(GP) monoclonal antibodies (TALS 828.179) can submit a request. Please note we have a new application portal. Learn more here.

Additionally, the two hybridoma clones have been deposited at the Developmental Studies Hybridoma Bank (DHSB) and can be accessed by sending a request to Target ALS at Manish Raisinghani. The supernatant from both clones (TALS 828.179 and TALS 828.66) work similarly in validation assays and can be accessed by contacting DHSB directly.

Mouse Vacht Polyclonal Antibody:

The antibody is available to ALS researchers worldwide. Investigators can request up to 10 aliquots (each aliquot contains 20 μl of the antibody).

Interested investigators can submit a request. Please note we have a new application portal. Learn more here.

Rabbit Polyclonal TDP-43 Antibody:

Rabbit polyclonal TDP-43 antibody (Proteintech #10782-2-AP) is available to academic and industry scientists conducting ALS research (for research use only). The antibody lot has been validated as the capture antibody in ELISA immunoassays. Researchers may request one (1) 150 uL aliquot (concentration 150 ug/mL). Submit a request. Please note we have a new application portal. Learn more here.

Rabbit Monoclonal pTDP-43 Antibody (Ser409/410):

Purified rabbit monoclonal antibody recognizing the pathological Serine 409/410 sites on TDP-43 is available at Developmental Studies Hybridoma Bank (DSHB) to academic and industry researchers (antibody also known as 2H610). This antibody recognizes pTDP-43 in mouse and human tissue/samples. Please request the antibody directly from DSHB and let Target ALS know when you have made your request.   

New Target ALS Application Portal

We are in the process of changing our online grant application portal.

  • You will need to create a new user account, called a Blackbaud ID, even if you have applied to our grants in the past.
  • You will be able to share your applications with co-applicants (consortium members) or other key stakeholders in your organization.
  • If you have a current Target ALS grant, you will not see it in this new application portal (we’re working on unifying them).
  • Add noreply@yourcause.com to your safe senders list to make sure you receive our emails and notifications. 

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We are a 501(c)(3) public charity (EIN: 81-0756743), eligible to receive tax-deductible contributions that directly support our mission to break down barriers to ALS research to find effective treatments.

The Target ALS (TALS) website is intended for informational purposes only. Opinions expressed may not be that of TALS or its employees. For more information about our digital policies, click here.

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Target ALS Foundation
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